Pico is a living testimony to the Cycle of Wine in the Azores. To know this story, one may explore, and savor, the small stone enclosures which spread from Lajido da Criação Velha up to Lajido de Santa Luzia, the "border area" of Pico's Vineyard Culture Protected Landscape. The austerity of the vineyard landscape and the viticultural ingrained experiences of the people of Pico contributed to the classification of this heritage as World Heritage by UNESCO.

The Wine Route on Pico Island starts and finishes in Vila da Madalena. The experience begins with a visit to the Wine Museum and proceeds with a visit to Lajido de Santa Luzia, one of the country vineyard landscapes classified as World Heritage by UNESCO.
The route to the former nucleus of wineries of Baia de Canas, in Prainha, includes a visit to the winery Adega da Buraca - a museum and venue for food and wine tasting.
The route continues to Engrade, a nucleus of wineries located in Piedade, and then to the coastal areas south of the island which cover the landscape areas classified as World Heritage by UNESCO, namely: São Mateus - with a nucleus of wineries; Candelaria - The winery A Rodilha and the nucleus of wineries in Lugar dos Fogos; and Criação Velha - Lajido da Criação Velha is a nucleus, whose vineyard landscape is classified by UNESCO.
The Wine Route ends with a visit to the Cooperative Wine Cellar of Pico.

The wine produced from the Verdelho grape variety, the result of hard work on the hard volcanic soil, has four centuries of uninterrupted production in Pico. In addition to Verdelho grapes, high-quality wines produced in a protected area currently include Arinto and Terrantez grapes.